One of the biggest things that we worry about in cardiology is depositing, plaquing (cholesterol) or inflammation within the system
doi:10.1016/S0167-0115(02)00157-X 31
Weight-loss drugs may not be suitable for all and can be associated with side effects such as constipation (difficulty passing stools), nausea, vomiting, headache, fatigue, diarrhea, mood changes, palpitations (irregular heartbeat), etc
Fatigue or mild headache may occur in some patients during the first day, though these symptoms are less common than gastrointestinal effects
Neuropharmacology 2019, 153: 112
[3] [4] Many patients find room temperature storage more comfortable for injections, as cold medication can cause injection site discomfort