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Mitochondrial production of superoxide anions and its relationship to the antimycin insensitive respiration

Decreased G6PD activity can trigger hemoglobin denaturation (Heinz body and bite cell in blood smears) and membrane damage (hemolysis) in RBCs

The rescue of cell viability by Sp was measured by following a similar treatment regimen as described above for ROS profiling of the cells

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MAPK stress cascades (JNK/p38) and ASK1: Depletion of GSH or oxidative shifts favor activation of stress MAPKs

While much of the data originates from animal and cell models, results are consistently positive for reducing inflammation, improving healing time, and increasing mobility