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PMID: 27499788

The principal limitation of our study was that it is based on modelled data, though as outlined above, our results show good alignment with clinical studies, and model-based PK/PD simulations are a common way to evaluate formulation doseeffect relationships for comparative analysis in the absence of head-to-head studies [24]

EVIDENCE GRADES 12-week Metabolic Pharmaceuticals Phase 2b at 1 mg/day did not meet primary weight-loss endpoint

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