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Whether a probiotic can boost GLP-1 levels enough to produce meaningful weight loss is still being studied

doi:10.1016/j.jcte.2024.100340 Mammoser G

Roche (via its acquisition of Carmot) has also been developing a small molecule oral drug, CT-996, but its progress has been stunted by poor tolerability

MACE, major adverse cardiovascular event

Suicidality: under active investigation Regulatory bodies, including the European Medicines Agency, have been reviewing a potential association between GLP-1 drugs and suicidal ideation

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