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CstMYB1R1, a REVEILLE-8-like transcription factor, regulates diurnal clock-specific anthocyanin biosynthesis and response to abiotic stress in Crocus sativus L

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This seemingly small change has a massive impact: it increases its potency by up to 10x in certain tissues and dramatically enhances its affinity for IGF1 receptors in damaged muscle cells

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Finally, while the focus of this investigation has centered on effects of inhibiting IGF-1 binding to the IGF-1R and HybridRs, L2-Cmu also interferes with IGF-2 binding to these receptors