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However, further research, particularly randomized controlled trials, is needed to fully elucidate the impact of vitamin D supplementation on cerebrovascular disease prevention and management [123]

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Observations from LVAD patients also suggest that while many experience normalization of LV chamber geometry, changes in the ECM and the ratio of LV wall thickness to LV wall radius may not return to normal 37

doi: 10.1074/jbc.M116.770974 111 SantosMde SousaM

Teriparatide has the strongest clinical evidence by far, with FDA approval and robust trial data showing fracture risk reduction and accelerated healing