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Several phytochemicals, including epigallocatechin-3-gallate, capsaicin, silymarin, indole-3-carbinol, proanthocyanins, curcumin, resveratrol, luteolin, apigenin, and genistein may be found in fresh fruits, vegetables, roots, and herbs

Of these, the role of BDNF has generated interest among nutritionists because it has been suggested that some food components (e.g., docosahexaenoic acid and curcumin) may act as neuroprotectants by affecting the levels of this neurotrophin in the brain (Wu et al., 2004

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De la Luz-Cuellar YE, Rodrguez-Palma EJ, Franco-Enzstiga et al (2019) Blockade of spinal 5-GABAA receptors differentially reduces reserpine-induced fibromyalgia-type pain in female rats