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injections of 100 nmol kg 1 PYY analogue ( n = 7 mice and n = 6 cages), 100 nmol kg 1 PYYMK-801 ( n = 7 mice and n = 4 cages), 100 nmol kg 1 GLP-1MK-801 ( n = 7 mice and n = 5 cages) or vehicle (isotonic saline, n = 7 mice and n = 4 cages) for 6 days

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While targeting the gut microbiota to alleviate neuroinflammation has become an integral component of perioperative care, future investigations elucidating the molecular mechanisms underlying gut microbiota modulating neuroinflammation may be necessary for the discovery of novel drug targets for PND