A separate check in the NIHs All of Us program found the main efficacy signal again, which strengthened confidence in the result
There are also single reports that a disorder of local (rather than plasma) lipoprotein metabolism in the central nervous system and cerebrospinal fluid is most likely the cause of decreased supply of cholesterol necessary for the recovery of myelin sheaths, which is probably associated with neurodegenerative diseases [382]
*Correspondence: Ying Liang, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
Adverse effects include muscarinic symptoms (e.g., gastrointestinal upset, increased secretions) and nicotinic effects (e.g., muscle cramps, fasciculations, weakness)
Ohashi K, Kim JH, Hara H et al
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