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Past medical history includes but not limited to urinary incontinence, hypertension, GERD, and osteoarthritis

[1] [2] These effects result primarily from the medication's mechanism of slowing gastric motility

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However, the bioequivalence criterion for the AUC was met for ethinylestradiol in all cases, and the AUC for the progestin component was either unaffected or showed approximately 20% higher mean exposure, which is not considered to affect the safety or efficacy of the combined pills

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