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A randomized, double-blind, placebo-controlled trial in 60 Thai medical students found that glutathione (500 mg/day for 4 weeks) reduced melanin index scores at multiple body sites compared to placebo (Arjinpathana & Asawanonda, J Dermatolog Treat, 2012) [61]

Suppression of tumor cell lactate-generating signaling pathways eradicates murine PTEN/p53-deficient aggressive-variant prostate cancer via macrophage phagocytosis

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Clinical studies confirm that chronic treatment with AOD9604 showed no adverse effect on insulin sensitivity, making it a metabolically selective approach to body composition optimization under medical supervision

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