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NHS treatment guidance describes a loading course followed by maintenance injections every two to three months for many people, while a diet-related deficiency may need less

As examples, some of these predictions are stated here: Under conditions of B12 insufficiency, excess folic acid intake will cause the following: Diversion of holoTC from serum to hemopoietic cells to support reticulocyte proliferation Loss of holoTC in urine due to interference of its reuptake by the megalin-receptor complex in the renal tubules Reduced availability of holoTC to the liver, brain, and other tissues due to its diversion to the hemopoietic system and loss in the urine

These melanocytes require adequate nutrition and cellular energy to function optimally

How does B12/MIC work

In chemotherapy, it helps protect normal cells from drug damage

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