Here are some key research findings on GHK-Cu: Collagen production: In a placebo-controlled study, GHK-Cu improved collagen production in 70% of participants, outperforming both vitamin C cream and retinoic acid Skin quality: A 12-week facial cream trial on 71 women with photoaging showed improved skin laxity, clarity, firmness, and increased skin density and thickness Wrinkle reduction: A 2016 study in the Journal of Aging Science found GHK-Cu in nano-carrier formulation reduced wrinkle volume by 31.6% compared to a commercial peptide product Broader effects: Promotes angiogenesis, supports nerve outgrowth, and demonstrates antioxidant and anti-inflammatory activity in cell culture and animal models GHK-Cu can be administered by subcutaneous injection or topical application, with injectable forms offering higher bioavailability

Unexpectedly, and in contrast to observations in fibroblasts, ACLY and ACSS2 double knockout (DKO) cancer cells remain viable and proliferate, maintain pools of cytosolic acetyl-CoA, and are competent to acetylate proteins in both cytosolic and nuclear compartments
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By Matthew Solan Executive Editor, Harvard Men's Health Watch image: Celso Pupo Rodrigues | Dreamstime.com