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J.TaoL.et al (2011)

Studies show that 5-amino-1-methylquinolinium injection inhibits NNMT, normalizes nicotinamide metabolism, elevates NAD+, reduces oxidative stress in cells, suppresses apoptosis, preserves cell function, and promotes insulin secretion, supporting longterm glycemic control

As autophagy-related genes are highly expressed in early AD, enhanced autophagy may be a promising research area for achieving neuroprotection in AD patients (Moujalled et al., 2021)