The firm has not published data beyond the press release, but it appears that those who take GLP-1s have much higher costs in the first year, and their inflation rate in year two is lower than those not on GLP-1s
They are placing the next bet before the current bet has finished paying out
Balance between on- and off-target effects of the dual GLP1/E agonist, and the concurrence of desensitization at very high doses, might contribute to this phenomenon
Not a rough estimate
We still face several challenges: We need large-scale, randomized controlled trials specifically in RA, psoriasis, and PsA populations We need to understand the long-term effects of these drugs in autoimmune conditions We need to determine the optimal dosing and treatment duration for these new indications What This Means for You: A Personal Note As your rheumatologist, my primary concern is your well-being
For example, a 2025 study showed an average loss of 7.9 to 12 lbs in PCOS patients