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Mice exposed to chronic unpredictable mild stress (CUMS) for 6 weeks showed increased hypothalamic corticotropin-releasing hormone concentrations, elevated corticosterone levels and increased blood ammonia, which corresponded with anxiety-like behaviors, demonstrating HPA axis involvement in anxiety pathogenesis (Jia et al., 2024)
Regulation of neuronal oxidative and nitrosative stress by endogenous protective pathways and disease processes
Age slower
One hypothesis regarding depressive disorders is based on a decrease in serotonergic activity ( A decrease in the level of SER can be caused by a decrease in consumption of food rich in proteins, or by redirecting the catabolism of tryptophan to the kynurenine pathway
Emodin attenuates bleomycin-induced pulmonary fibrosis via anti-inflammatory and anti-oxidative activities in rats
ROS are generated by mitochondria as a byproduct of ATP production
