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Joseph Brewer evaluated 112 patients with a prior diagnosis of ME/CFS

Rotin D, Staub O

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In the protein processing in the ER pathways, 2 genes ( Bcsec62 and Bcero1 ) related to correct or misfolded protein processing and 14 genes ( BCIN_02g04920, BCIN_15g04190, BCIN_15g02550, Bcubc6, Bcfes1, Bcotu1, BCIN_10g00300, Bcufd2, BCIN_03g09290, Bcsec63, Bcdsk2, Bcrad23, Bcpng1 , and BCIN_08g04560 ) from the ER-associated degradation (ERAD) were significantly upregulated in our study (Supplementary Table 7)