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Weight loss was an adverse effect associated with zonisamide treatment in clinical trials for epilepsy

This action helps the body burn more fat by utilizing it for energy

The mouse research that established its mechanism and preclinical effects used subcutaneous injection at a fixed research dose (20 mg/kg, three times daily) a research-animal protocol, not a human administration guide

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Visit your doctor and dietician regularly to monitor your progress

Mechanistically, NNMT suppression increased adipose SAM and NAD, upregulated polyamine flux enzymes (ODC, SSAT), and altered histone methylation consistent with a shift toward oxidative metabolism [2]