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To further investigate the relative contributions of MOR-expressing enteric versus MOR-expressing PVN Glu neurons in morphine-induced constipation, we infused AAV-DIO-shMOR-EGFP or AAV-DIO-EGFP control virus into the PVN of VgluT2-Cre mice, then induced constipation by i.p

doi: 10.3389/fphar.2017.00904

Research-grade material varies in purity, actual copper stoichiometry, and sterility between suppliers and lots

Some studies describe occasional localized redness or mild irritation during topical research applications, while systemic toxicity has not been observed at commonly investigated research concentrations

R., Na, J