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Effects of semaglutide and tirzepatide on bone metabolism in type 2 diabetic mice

A small pilot study in 20 human patients (aged 5075, with obesity and knee osteoarthritis) found that those receiving semaglutide alongside standard treatment showed an average 17% increase in cartilage thickness on MRI after 24 weeks, compared to less than 1% in the control group

Oral glutathione supplements lose many benefits during the digestion process

Preclinical studies suggest good tolerability, but comprehensive human trials are needed to establish safety profiles

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