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Clinical trials have utilized doses ranging from 1 mg per day up to 30 mg per day in divided doses for various administration routes, demonstrating safety across a wide dose spectrum

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If, however, the volume of the red methyl-B12 shot is small, the urine will not show red or pink even though the methyl-B12 is filtered through the kidney into the urine within the same 30-45 minutes after being injected