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Importantly, the study confirmed that AOD-9604 displayed a very good safety and tolerability profile indistinguishable from placebo, with no treatment-related serious adverse events or study withdrawals occurring

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Gene-therapy animal model to evaluate the long term effect and the efficiency of using the multiple drug resistance gene retroviral vectors in conferring the chemo resistance phenotype upon early progenitor cells

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(2017) CHAC1 degradation of glutathione enhances cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells via the GCN2-eIF2-ATF4 pathway, Oncotarget , 8 , 114588-114602, doi: Lei, P., Bai, T., and Sun, Y