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The emergence of GLP-1 as a modulator of reward, stress, inflammation, and metabolic function represents a promising frontier in addiction medicine

Q J Exp Physiol (1987) 72(4):54959

Full receptor saturation, achieved at higher doses, produces maximal appetite suppression but also maximal GI effects

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The most well-known examples of regulated peptides are GLP-1 medications like Ozempic, as well as insulin

CJC-1295 with DAC includes a drug-affinity-complex modification that binds albumin and extends activity