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( Minnetti M, Sada V, Feola T, Giannetta E, Pozza C, Gianfrilli D, Isidori AM

Quercetin improves the imbalance of Th1/Th2 cells and Treg/Th17 cells to attenuate allergic rhinitis

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It is also involved in muscle function, immune health, and cellular processes

some peptide reaches systemic circulation (supported by systemic effect reports) but at likely reduced bioavailability compared to parenteral

Conclusion This review synthesizes current evidence to summarize the therapeutic potential and underlying mechanisms of nanozymes in IMIDs, while highlighting key challenges and future directions to guide the development and clinical translation of nanozyme-based therapies