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the side chains of Ser2 and Arg11 and the main chain carbonyl of Phe4 of ghrelin are hydrogen-bonded by the main chain carbonyl groups of F290 ECL2 and S308 7.38 and the side chain of Y106 of GHSR, respectively (Fig

2006;290:E1118E1123

Statin intolerance should be defined as inability to receive statin therapy adequate (with respect to the product or the dose) to the existing cardiovascular risk [8]

Diabetes Care 48(7):11011111 Coskun T, Sloop KW, Loghin C, Alsina-Fernandez J, Urva S, Bokvist KB, Cui X, Briere DA, Cabrera O, Roell WC, Kuchibhotla U, Moyers JS, Benson CT, Gimeno RE, DAlessio DA, Haupt A (2018) LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept

Finally, for HbA1c, all studies were included in the analysis as this outcome was consistently measured across all trials