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According to the Common Terminology Criteria for Adverse Events (CTCAE) [75] , AEs are classified into grades of severity

Any uninsured patient considering long-term GLP-1 therapy should undergo baseline metabolic and renal assessment

Timing Optimization Some patients find that administering semaglutide on a day when they can rest if needed (such as Friday evening or Saturday morning) helps manage initial side effects

Results are not typical and vary by patient

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Some common side effects are mild reactions at the injection site, short-term tiredness, or feeling sick sometimes during the first few doses