When patients do not respond adequately to a TNF inhibitor, there is little evidence to suggest that increasing the dose may be beneficial
The SmPCs for all GLP-1 receptor agonists advise caution in patients with a history of pancreatitis, though they are not absolutely contraindicated
But it is an important consideration, given that the research published so far shows that when patients discontinue using these medications, their appetite returns, and the majority regain some or all of the weight they initially lost
[DOI] [PMC free article] [PubMed] [Google Scholar] 47.Morton GJ, Schwartz MW
Triamcinolone acetonide extended-release: a review in osteoarthritis pain of the knee
Cleveland Clinic explains that GLP-1 agonists can make food stay in the stomach longer and reduce appetite, but they can also cause digestive side effects like nausea and constipation, which makes food choices more important