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The secretion of inflammatory cytokines, such as tumor necrosis factor (TNF)-a, would lead to neuroinflammation and migraine episodes by increasing the cellular permeability and interactions

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POTS is also directly related to Hcy levels, at least in the young (Li et al., 2018)

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If the interacting protein that youre analyzing also binds to the GST only control, then this may be through non-specific interactions to the beads or to GST (Figure 8)