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Back Holst, JJ (26 April 2019) 'From the Incretin Concept and the discovery of GLP-1 to today's diabetes therapy', Frontiers in Endocrinology , 10
Ghrelins most characterized effects are: (i) its ability to stimulate GH secretion, likely of relevance for glucose homeostasis and energy balance
The suggested dithiol mechanism for the reduction of EcRNR by EcGrx1 comprises a dithiol-disulfide exchange reaction followed by the stepwise reduction of EcGrx1(S 2 ) and EcGrx1(SSG) by two molecules of GSH (Fig