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Reduced renal clearance, increased elimination half-life ( t ), and high maximum plasma drug concentration ( C max ) values of antidiabetic drugs may lead to high and prolonged drug exposure [11,12,13,14,15,16,17]

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1983 Mar 31;756(2):196-203

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Clinical data shows patients taking oral semaglutide achieve meaningful weight loss comparable to injection protocols, making it an attractive option for those preferring non-injection therapy