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The process of wound healing is intricate and cascaded, particularly in chronic wounds like severe burns and diabetic wounds, where unfavorable endogenous or external variables can impede the healing process by interfering with the regulation of inflammation [37]

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EGCGs interaction with cellular pathways is crucial in HD treatment, as it activates AMPK signaling, which plays a vital role in cellular energy homeostasis and autophagy regulation

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Studies show certain derivatives exhibit enhanced neuroprotective effects through stronger binding to therapeutic targets and improved cellular uptake [126]