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Both DNA and mRNA vaccines fall under this category and are being pursued in the context of the COVID-19 pandemic
Moderate weight loss is sufficient to affect thyroid hormone homeostasis and inhibit its peripheral conversion
Improved understanding of the contributors to the observed decrease in dementia incidence, quantifying the role of changes in cardiovascular risk profiles and educational attainment for example, may open opportunities to accelerate prevention efforts and to better use public health investments not specifically targeted to AD/ADRD (e.g., initiatives aimed at improving cardiovascular health)
These alterations can ultimately lead to both diastolic and systolic cardiac dysfunction, potentially resulting in heart failure (Moran et al., 2022)
elegans and ameliorated mutiple aging-related phenotypes, including enhanced resistance to oxidative and thermal stress, improved motility, pharyngeal pumping, defecation rhythm, and reduced lipofuscin/lipid accumulation