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Brodt et al, 2000) and truncated soluble IGF-1R (D'Ambrosio et al, 1996) are two related strategies to block IGF-1R

The dramatic increase in awareness and novel utilization of oral nutraceuticals over the past 10 years has been remarkable [7]

Given its role in catalyzing the conversion of pyruvate to lactate in glycolytic cancer cells and the observation that LDHA deficiency results in only relatively mild symptoms, such as exertional myopathy, LDHA represents a pivotal and safe therapeutic target (150,167)

The tripeptide GHK-Cu has become a hot compound in regenerative research, attracting scientific attention for its unique molecular properties

In KCs, autophagy may affect functional polarization, 165 while in activated HSCs, it may sustain a pro-fibrotic phenotype