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These enzymes not only maintain basal metabolic flux through their catalytic activity but also participate in epigenetic regulation, transcription factor activation, redox homeostasis, and the modulation of cell death pathways, thereby acting as upstream drivers of mitochondrial metabolic reprogramming [95]

Therefore, the characteristic Zn 2p signals observed in XPS and the corresponding changes in the O 1 s binding energy further confirmed the presence of coordinated Zn and phenolic hydroxyl groups in the composite material (Fig

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