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Whether that multiple is justified depends entirely on whether the research question requires glucagon receptor engagement or whether the 4.3 percentage point weight loss advantage over tirzepatide (24.2% vs 20.9%) is scientifically meaningful for the study design

Efficacy unclear

Negative reviews cluster around two complaints

Iiritano, A

2012 (Indian J Psychol Med) RCT, 64 adults with chronic stress

Data Charting Relevant information from each included study was extracted using a data charting form that captured the following fields: author(s), year of publication, country of origin, whether the combination was an add-on or simultaneously used, study population characteristics relevant to the outcomes, and sample size, study design, intervention or exposition type and details of these, comparator, outcomes and their specifics, adverse effects reports, and key findings related to the scoping review questions