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The normal requirement is less than 2 milligrams (mg) a day, yet many B6 supplements are 100 mg or more

"Mutations in the enzyme glutathione peroxidase 4 cause Sedaghatian-type spondylometaphyseal dysplasia"

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Taken together with precedent from oncology, the overall evidence indicates that Erastin has clear therapeutic potential for EMS, provided drug delivery preferentially targets lesions while sparing healthy tissue