F.et al (2022)
The authors hypothesized a neuroprotective effect of hyperinsulinism in obese diabetic patients which could be attributed to counteracting the decrease in cell-surface gamma-aminobutyric acid receptors, reduction of glutamate, and through the regulation of the Phosphoinositide 3-Kinase (PI3K) pathway
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Cephalalgia 30 , 11791186 (2010)
Continuous administration does not seem to provide additional benefit and may actually diminish the compound's effectiveness over time
2, pp 500 [online] Available at: Larsson, S.C., Hakansson, N., and Wolk, A