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It plays a critical role in the maintenance of muscle health and function by allowing the extraction of nutrients, oxygen, and hormones such as insulin from the blood into the muscle interstitium and the removal of metabolic by-products from the muscle cells to the circulation with subsequent clearance by the liver and kidney (Figure 1)

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By the time you inject, you're administering 6075% of the intended dose, clearance appears artificially fast, and results don't replicate