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Observed effects in human trials Reported adverse events across the IV and oral trials included headache, fatigue, dizziness, nasopharyngitis, diarrhea, flatulence, increased appetite, nausea, and back pain

B12 injections help improve concentration, boost energy levels, and regulate mood

Range of motion expands, previously painful movements become tolerable, and daily activities that were modified due to pain can be resumed

Novel small molecule inhibitors of nicotinamide N-methyltransferase (NNMT)

PepCal Mix (Sciex, Concord, Ontario, Canada) was used to ensure steady MS and tandem MS (MS/MS) calibrations during the whole analysis timeframe

Keep it in its original packaging and out of reach of children