Why did you decide to create a GLP-1 supplement
Postprandial hyperinsulinaemia Less suppression of insulin secretion in the presence of hypoglycaemia and greater sensitivity of cells to increased blood glucose levels have been described after GBP7, mediated both by intestinal hormonal factors (increase in GLP-1 secretion)8,9 and by non-hormonal factors68 (postprandial elevation of unconjugated bile acids)7, which will be accompanied by an earlier and more intense peak of postprandial insulinaemia.7,8 One of the first hypotheses proposed was the increase in the mass of pancreatic cells with nesidioblastosis, as a result of the exaggerated secretion of GLP-110
doi:10.1038/s41591-023-02669-x Nunn E, Jaiswal N, Gavin M, et al
Researchers interested in peptide combinations with retatrutide typically look at non-overlapping mechanisms
Proven Weight Loss: Clinical studies, including the SURMOUNT-1 trial, have shown that Mounjaro can help people with obesity (without diabetes) lose an average of 15% to over 20% of their body weight
Muscle preservation, bone density maintenance, cardiovascular adaptation, and metabolic health all require attention during aggressive weight loss
