Gastric Emptying, Aspiration Risk, and Anesthesia Considerations Delayed gastric emptying from GLP-1 therapy increases perioperative aspiration riskstomach contents entering the lungs during anesthesia induction
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Additionally, increasing daily non-exercise activity, like taking stairs or standing more, contributes to overall calorie burn
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For a lyophilized powder, a few hours may have a minimal impact, but for a reconstituted solution, significant potency loss can occur quickly
What the SURMOUNT-5 Trial Means for UK Patients The publication of SURMOUNT-5 in the NEJM in 2025 was a landmark moment the first time tirzepatide and semaglutide were directly compared in a randomised controlled trial for weight management