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The placebo group barely changed

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Captopril, an angiotensin-converting enzyme inhibitor, is widely used in clinical practice to treat hypertension, MI, and congestive heart failure and is effective in attenuating left ventricular (LV) dilatation, ameliorating LV ejection fraction and improving cardiovascular morbidity and mortality [237, 238]

All experimental protocols were approved by the Local Ethic Committee of Animal Experiments of Erciyes University (approval n 22/176 date: 08.08.2022) in Turkiye

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patients receiving semaglutide in combination with an insulin secretagogue (e.g., sulfonylurea) or insulin may have an increased risk of hypoglycemia, including severe hypoglycemia