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This model demonstrates auxological and biochemical similarities to human GHD caused by POU1F1 mutations, such as SS, low IGF-I levels, and increased adiposity, and responds to GH treatment with an increase in body weight, length, serum IGF-I levels, and body composition (e.g., increased lean mass relative to fat mass)

Platelet glutamate receptors have been shown to have heightened sensitivity in major depression, schizophrenia and other psychoses [104106]

Temperature fluctuations significantly reduce peptide stability, so avoid storing vials in refrigerator door compartments where temperatures vary with each opening

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For each experiment, same-aged aphids (age depending on experiment) were dissected in cold PBS to obtain embryos or bacteriocytes, and these were fixed in 3.7% formaldehyde in PBS on ice for 2025 min

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