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Similarly, DSePA, another interesting organoselenium compound, has shown potent efficacy as a lung-specific radiomitigator through inducing the expressions rather than mimicking the activities of seleno-GPxs, thus warranting future clinical studies [61, 62]

Intracellular ROS levels were assessed using 2,7-dichlorodihydrofluorescein diacetate (DCFH-DA) staining and flow cytometry, revealing a 9.1-fold increase in ROS production in methamphetamine-treated SH-SY5Y cells

Tesofensine also increased blood pressure, heart rate, and frequency of mood changes

Cancer Cell 27 , 211222 (2015)

Cells were stained and analysed with a FACS analyser as stated above

doi: 10.1021/acs.analchem.7b04672