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If its acquired, the symptoms are caused by a different disease

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These effects occurred more frequently at higher doses and were generally consistent with the known side effect profile of incretin-based therapies

As supplements which contain the enzyme DAO which breaks down food sourced histamine exist, investigations also could include consumption of high histamine foods both with and without the supplementation of DAO to see if symptoms diminish with the enzyme use

Tuck CJ, Reed DE, Muir JG, Vanner SJ