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What are the drawbacks of tirzepatide

A few participants with a BMI above 27 kg/m participated, but only if they had an additional weight-related health issue, such as hypertension or hyperlipidemia

At the 12mg dose, participants lost an average of 24.2% of their body weight in just 48 weeks

A published study examining appetite and eating behaviors during retatrutide treatment in the phase 2 trial found that 31 of 36 retatrutide-treated participants (86%) reported changes in eating behaviors within the first eight weeks of treatment