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10.1016/j.vph.2012.11.002 7 BernardC

Doran KS, Banerjee A, Disson O, Lecuit M (2013) Concepts and mechanisms: crossing host barriers

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Fundamental questions remain regarding the future prospects of this line of drug development, including questions concerning safety and tolerability, efficacy, doseresponse relationships and therapeutic mechanisms

It has no receptor-mediated effect on appetite, satiety hormones, or gastric motility