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The clinical trials included in the review had a high degree of heterogeneity in terms of substance types, patients' characteristics, and types and doses of the administered GLP-1 receptor agonists

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Similar content being viewed by others Introduction Class B G protein-coupled receptors (GPCRs), whose endogenous ligands are peptide hormones, are key mediators of normal human physiology and serve as valuable drug targets for many diseases including diabetes, metabolic syndrome, osteoporosis, migraine, depression, and anxiety 1

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Makkar RR, Chikwe J, Chakravarty T, Chen Q, OGara PT, Gillinov M, et al