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doi: 10.1155/2013/424163 202 PaparoSRFerrariSMPatrizioAEliaGRagusaFBotriniCet al

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We hypothesized that acute mild stress would have little effect on its own, but when combined with Glud1 deficiency would induce long-term changes in mPFC gene expression patterns

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In this context, another study showed that in streptozotocin-induced diabetic rats, Que (100 mg/kg) inhibits oxidative damage by increasing SIRT1 expression and decreasing levels of NF-B, a SIRT1 substrate (Iskender et al., 2017)