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Semaglutide does not cause euphoria or cravings for the drug and is administered once per week

[DOI] [PubMed] [Google Scholar] Hwang P.S., Machek S.B., Cardaci T.D., Wilburn D.T., Kim C.S., Suezaki E.S., et al

Menstrual irregularities are not listed as a recognised adverse reaction in the Summary of Product Characteristics (SmPC) approved by the Medicines and Healthcare products Regulatory Agency (MHRA), though some women have reported changes to their menstrual cycle while taking this medication

250 This study highlights that after GLP-1 has been processed by DPP-IV it may still have physiological functions and is not inactivated as current dogma suggests in humans

Your prescriber may need to adjust your starting dose or titration schedule to account for these individual variations